Ontology highlight
ABSTRACT:
SUBMITTER: Fares J
PROVIDER: S-EPMC8105040 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Brain : a journal of neurology 20210501 4
Brain metastases are the most common type of brain tumours, harbouring an immune microenvironment that can in principle be targeted via immunotherapy. Elucidating some of the immunological intricacies of brain metastases has opened a therapeutic window to explore the potential of immune checkpoint inhibitors in this globally lethal disease. Multiple lines of evidence suggest that tumour cells hijack the immune regulatory mechanisms in the brain for the benefit of their own survival and progressi ...[more]