Single-trial decoding of movement intentions using functional ultrasound neuroimaging.

ABSTRACT: New technologies are key to understanding the dynamic activity of neural circuits and systems in the brain. Here, we show that a minimally invasive approach based on ultrasound can be used to detect the neural correlates of movement planning, including directions and effectors. While non-human primates (NHPs) performed memory-guided movements, we used functional ultrasound (fUS) neuroimaging to record changes in cerebral blood volume with 100 μm resolution. We recorded from outside the dura above the posterior parietal cortex, a brain area important for spatial perception, multisensory integration, and movement planning. We then used fUS signals from the delay period before movement to decode the animals' intended direction and effector. Single-trial decoding is a prerequisite to brain-mac

SUBMITTER: Norman SL 

PROVIDER: S-EPMC8105283 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature