Epidemiology and evolution of Middle East respiratory syndrome coronavirus, 2012-2020.

ABSTRACT:

Background

The ongoing transmission of the Middle East respiratory syndrome coronavirus (MERS-CoV) in the Middle East and its expansion to other regions are raising concerns of a potential pandemic. An in-depth analysis about both population and molecular epidemiology of this pathogen is needed.

Methods

MERS cases reported globally as of June 2020 were collected mainly from World Health Organization official reports, supplemented by other reliable sources. Determinants for case fatality and spatial diffusion of MERS were assessed with Logistic regressions and Cox proportional hazard models, respectively. Phylogenetic and phylogeographic analyses were performed to examine the evolution and migration history of MERS-CoV.

Results

A total of 2562 confirmed MERS cases with

SUBMITTER: Zhang AR 

PROVIDER: S-EPMC8105704 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature