Application and outlook of topical hemostatic materials: a narrative review.

ABSTRACT: Bleeding complications can cause significant morbidities and mortalities in both civilian and military conditions. The formation of stable blood clots or hemostasis is essential to prevent major blood loss and death from excessive bleeding. However, the body's self-coagulation process cannot accomplish timely hemostasis without the assistance of hemostatic agents under some conditions. In the past two decades, topical hemostatic materials and devices containing platelets, fibrin, and polysaccharides have been gradually developed and introduced to induce faster or more stable blood clot formation, updating or iterating traditional hemostatic materials. Despite the various forms and functions of topical hemostatic materials that have been developed for different clinical conditions, uncontro

SUBMITTER: Zhong Y 

PROVIDER: S-EPMC8105794 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature