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A nomogram to predict survival in patients with acute-on-chronic hepatitis B liver failure after liver transplantation.


ABSTRACT:

Background

Individualized prediction of survival after liver transplantation (LT) for patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) has not been well investigated. This study aimed to develop a prognostic nomogram for patients with HBV-ACLF undergoing LT.

Methods

The nomogram was derived from a retrospective study of 290 patients who underwent LT for HBV-ACLF at the Third Affiliated Hospital of Sun Yat-sen University between January 2012 and December 2017. Concordance index and determiner calibration curve was used to ascertain the predictive accuracy and discriminative ability of the nomogram. The predictive performance of the nomogram was compared with that of Child-Pugh score, model for end-stage liver disease (MELD), MELD-Na, chronic l

SUBMITTER: Chen L 

PROVIDER: S-EPMC8105851 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature