Far from MCAR: Obtaining Population-level Estimates of HIV Viral Suppression.

ABSTRACT:

Background

Population-level estimates of disease prevalence and control are needed to assess prevention and treatment strategies. However, available data often suffer from differential missingness. For example, population-level HIV viral suppression is the proportion of all HIV-positive persons with suppressed viral replication. Individuals with measured HIV status, and among HIV-positive individuals those with measured viral suppression, likely differ from those without such measurements.

Methods

We discuss three sets of assumptions to identify population-level suppression in the intervention arm of the SEARCH Study (NCT01864603), a community randomized trial in rural Kenya and Uganda (2013-2017). Using data on nearly 100,000 participants, we compare estimates from (1) an u

SUBMITTER: Balzer LB 

PROVIDER: S-EPMC8105880 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature