Research progress of circRNA as a biomarker of sepsis: a narrative review.

ABSTRACT:

Objective

Explore the possibility of circRNAs as markers of sepsis.

Background

Sepsis is an abnormal immune response of our body to infection that can lead to organ failure and death. Although the research on sepsis has been extensive in the past few years, sepsis-associated morbidity and mortality are still increasing. Early diagnosis and early treatment are important for patients with sepsis. Although many markers, including procalcitonin and C-reactive protein, have been proposed as diagnostic indicators of sepsis, there are still challenges in the early diagnosis and treatment of sepsis due to the lack of sensitivity and specificity of these substances. Recently, a large number of studies have found that circular RNAs (circRNAs) participate in a variety of biological fun

SUBMITTER: Qi L 

PROVIDER: S-EPMC8106021 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature