Prevalence and clinical characteristics of antibiotics associated drug induced liver injury.

ABSTRACT:

Background

The use of antibiotics increases recently. Accordingly, the incidence of antibiotics associated with drug induced liver injury (DILI) also increases. The purpose of this study is to evaluate the proportion and the clinical characteristics of antibiotic associated with DILI.

Methods

This study is a retrospective study of analyzed adult patients who were referred to the department of hepatology for the elevation of liver function tests and the frequency of elevated liver enzyme of patients with prescribed antibiotics during the same period at outpatient setting as a validation set.

Results

Antibiotics associated with DILI (64.0%) are the most common reason agent among consulting to hepatology department. Rheumatoid arthritis related drugs (11.0%), health supp

SUBMITTER: Park JH 

PROVIDER: S-EPMC8106034 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature