Engineering oleaginous yeast Rhodotorula toruloides for overproduction of fatty acid ethyl esters.

ABSTRACT:

Background

Production of biofuels and green chemicals by microbes is currently of great interest due to the increasingly limited reserves of fossil fuels. Biodiesel, especially fatty acid ethyl esters (FAEEs), is considered as an attractive alternative because of its similarity with petrodiesel and compatibility with existing infrastructures. Cost-efficient bio-production of FAEEs requires a highly lipogenic production host that is suitable for large-scale fermentation. As a non-model oleaginous yeast that can be cultured to an extremely high cell density and accumulate over 70% cell mass as lipids, Rhodotorula toruloides represents an attractive host for FAEEs production.

Results

We first constructed the FAEE biosynthetic pathways in R. toruloides by introducing various wax

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC8106135 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature