Comorbidities in Older Persons with Controlled HIV Infection: Correlations with Frailty Index Subtypes.

ABSTRACT: Frailty is prevalent in persons with human immunodeficiency virus (PWH), but factors predisposing older PWH to frailty remain uncertain. We examined factors associated with frailty and determined whether there were multiple frailty subtypes in older adults with controlled HIV infection. This was a cross-sectional outpatient study in an urban HIV clinic. Twenty-nine clinical indicators were extracted from medical records to compute a Frailty Index (FI) for 389 older (age 50+) PWH (range = 50-93; mean = 61.1, standard deviation = 7.2; 85% men) receiving HIV treatment in Calgary, Canada. We used regressions to identify factors associated with FI values. Latent class analysis was used to identify FI subtypes. Age, employment status, and duration of known HIV infection were the strongest predic

SUBMITTER: McMillan JM 

PROVIDER: S-EPMC8106245 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature