A multi-omics approach to lignocellulolytic enzyme discovery reveals a new ligninase activity from <i>Parascedosporium putredinis</i> NO1.

ABSTRACT: Lignocellulose, the structural component of plant cells, is a major agricultural byproduct and the most abundant terrestrial source of biopolymers on Earth. The complex and insoluble nature of lignocellulose limits its conversion into value-added commodities, and currently, efficient transformation requires expensive pretreatments and high loadings of enzymes. Here, we report on a fungus from the Parascedosporium genus, isolated from a wheat-straw composting community, that secretes a large and diverse array of carbohydrate-active enzymes (CAZymes) when grown on lignocellulosic substrates. We describe an oxidase activity that cleaves the major β-ether units in lignin, thereby releasing the flavonoid tricin from monocot lignin and enhancing the digestion of lignocellulose by polysacc

SUBMITTER: Oates NC 

PROVIDER: S-EPMC8106297 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature