Significance of indeterminate pulmonary nodules in resectable pancreatic adenocarcinoma-a review.

ABSTRACT:

Background

The clinical significance of indeterminate pulmonary nodules (IPN) in patients with resectable pancreatic adenocarcinoma (PDAC) is unknown. The rate of detection on IPN has risen due to enhanced staging investigations to determine resectability. IPNs detected on preoperative imaging represent a clinical dilemma and complicate decision-making. Currently, there are no recommendations on the management of IPN. This review provides a comprehensive overview of the current knowledge on the natural history of IPN detected among patients with resectable PDAC.

Methods

A systematic review based on a search in Medline and Embase databases was performed. All clinical studies evaluating the significance of IPN in patients with resectable PDAC were included. PRISMA guidelines w

SUBMITTER: Kuan LL 

PROVIDER: S-EPMC8106596 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature