Alcohol and Neural Dynamics: A Meta-analysis of Acute Alcohol Effects on Event-Related Brain Potentials.

ABSTRACT:

Background

An understanding of alcohol's acute neural effects could augment our knowledge of mechanisms underlying alcohol-related cognitive/motor impairment and inform interventions for addiction. Focusing on studies employing event-related brain potential methods, which offer a direct measurement of neural activity in functionally well-characterized brain networks, we present the first meta-analysis to explore acute effects of alcohol on the human brain.

Methods

Databases were searched for randomized laboratory alcohol-administration trials assessing brain activity using event-related potentials. Hedges' g coefficients were pooled using 3-level random-effects meta-regression.

Results

Sixty independent randomized controlled trials met inclusion (total N = 2149). Alco

SUBMITTER: Fairbairn CE 

PROVIDER: S-EPMC8106628 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature