Dataset Information
Anti-IL-5 therapies for chronic obstructive pulmonary disease.
Ontology highlight
ABSTRACT:
SUBMITTER: Donovan T
PROVIDER: S-EPMC8106745 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Publications
Anti-IL-5 therapies for chronic obstructive pulmonary disease.
The Cochrane database of systematic reviews 20201208
<h4>Background</h4>Exacerbations of chronic obstructive pulmonary disease (COPD) are a major cause of hospital admissions, disease-related morbidity and mortality. COPD is a heterogeneous disease with distinct inflammatory phenotypes, including eosinophilia, which may drive acute exacerbations in a subgroup of patients. Monoclonal antibodies targeting interleukin 5 (IL-5) or its receptor (IL-5R) have a role in the care of people with severe eosinophilic asthma, and may similarly provide therapeu ...[more]