Rapid high-resolution volumetric T₁ mapping using a highly accelerated stack-of-stars Look Locker technique.

ABSTRACT:

Purpose

To develop a fast volumetric T₁ mapping technique.

Materials and methods

A stack-of-stars (SOS) Look Locker technique based on the acquisition of undersampled radial data (>30× relative to Nyquist) and an efficient multi-slab excitation scheme is presented. A principal-component based reconstruction is used to reconstruct T₁ maps. Computer simulations were performed to determine the best choice of partitions per slab and degree of undersampling. The technique was validated in phantoms against reference T₁ values measured with a 2D Cartesian inversion-recovery spin-echo technique. The SOS Look Locker technique was tested in brain (n = 4) and prostate (n = 5). Brain T₁ mapping was carried out with and without k_z ac

SUBMITTER: Li Z 

PROVIDER: S-EPMC8107135 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature