Epidemiology, diagnosis and treatment of the malignant pleural mesothelioma, a narrative review of literature.

ABSTRACT: The malignant pleural mesothelioma is a very aggressive tumor which is arising from mesothelial cells and is associated with asbestos exposure. It is a heterogeneous cancer that shows a complex pattern of molecular changes, including genetic, chromosomic, and epigenetic abnormalities. The malignant pleural mesothelioma is characterized by a silent and slow clinical progression with an average period of 20-40 years from the asbestos exposure phase to the start of the symptoms. Unfortunately, to date, the therapeutic options are very limited, especially if the tumor is detected late. This narrative review provides an extended overview of the present evidence in the literature regarding the epidemiology, diagnostic pathways and treatment approaches of the malignant pleural mesothelioma. The t

SUBMITTER: Schumann SO 

PROVIDER: S-EPMC8107529 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature