Characteristics of unilateral main bronchus obstruction and differentiation from chronic obstructive pulmonary disease by spirometry.

ABSTRACT:

Background

Pattern of flow-volume (F-V) loop in unilateral main bronchus obstruction (UMBO) is under-represented and sometimes misinterpreted as chronic obstructive pulmonary disease (COPD).

Methods

A cross-sectional study was performed among patients with UMBO and COPD confirmed by bronchoscopy, radiographic imaging and spirometry from 2006 to 2019. Data were extracted from electronic medical records. Spirometry data and flow-volume curves (F-V curves) were analyzed. Expiratory F-V curve was classified as monophasic or biphasic according to the absence or presence of breakpoint separating two distinct slopes. Propensity score method was used to reduce the selection bias, and logistic analysis in combination with decision tree approach was performed to explore the difference

SUBMITTER: Sun W 

PROVIDER: S-EPMC8107564 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature