Outcomes of young patients diagnosed with locally advanced rectal cancer.

ABSTRACT:

Background

The incidence of rectal cancer is higher in the older population. In developed nations, there has been a rise in incidence in young onset colorectal cancer (CRC). We examined the outcomes of locally advanced rectal cancer (LARC) in younger patients (yRC) compared with older patients, using a retrospective audit.

Methods

All cases of LARC referred to two tertiary referral cancer centres in Western Sydney were examined. Patient demographics, presenting symptoms, treatment, relapse free survival (RFS), overall survival (OS) and progression free survival (PFS) were obtained. Under 50 years old was used as the cut-off age for defining yRC.

Results

All 145 consecutive patients were treated for LARC, including 28 in the yRC and 117 in the older patient group. Medi

SUBMITTER: Habib R 

PROVIDER: S-EPMC8107615 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature