Blood transfusions may adversely affect survival outcomes of patients with lung cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Despite common use in clinical practice, the impact of blood transfusions on prognosis among patients with lung cancer remains unclear. The purpose of the current study is to perform an updated systematic review and meta-analysis to evaluate the influence of blood transfusions on survival outcomes of lung cancer patients.

Methods

We searched PubMed, Embase, Cochrane Library, and Ovid MEDLINE for publications illustrating the association between blood transfusions and prognosis among people with lung cancer from inception to November 2019. Overall survival (OS) and disease-free survival (DFS) were the outcomes of interest. Pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were computed using the random-effects model. Study heterogeneity was evaluated w

SUBMITTER: Cho S 

PROVIDER: S-EPMC8107741 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature