Immediate outcomes in early life epilepsy: A contemporary account.

ABSTRACT:

Rationale

Early-life epilepsies (ELEs) include some of the most challenging forms of epilepsy to manage. Given recent diagnostic and therapeutic advances, a contemporary assessment of the immediate short-term outcomes can provide a valuable framework for identifying priorities and benchmarks for evaluating quality improvement efforts.

Methods

Children with newly diagnosed epilepsy and onset <3 years were prospectively recruited through 17 US hospitals, from 2012 to 2015 and followed for 1 year after diagnosis. Short-term outcome included mortality, drug resistance, evolution of nonsyndromic epilepsy to infantile spasms (IS) and from IS to other epilepsies, and developmental decline. Multivariable analyses assessed the risk of each outcome.

Results

Seven hundred sevent

SUBMITTER: Berg AT 

PROVIDER: S-EPMC8107814 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature