Opioid Use in Adults With Sickle Cell Disease Hospitalized During Vaso-Occlusive Crisis: A Systematic Review.

ABSTRACT:

Background

While pain is the hallmark of sickle cell disease (SCD), healthcare personnel are often ill-equipped to adequately treat patients who present in vaso-occlusive crisis (VOC). Although symptom severity varies from individual to individual, SCD is characterized by intervallic pain as a result of oxygen deprivation in tissues and organs. Regardless of pain severity, SCD patients are often viewed as drug seekers by healthcare personnel who have concerns regarding patients' dependence on opioids which may lead to addiction. The objective was to assess the types and amount of opioids used to treat VOC in comparison to Centers for Disease Control opioid prescription guidelines.

Methods

Literature search was conducted using CINAHL, PubMed, the Cochrane Library, Web of Scie

SUBMITTER: Osborne JC 

PROVIDER: S-EPMC8110229 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature