Key Characteristics of Nitrous Oxide-Induced Neurological Disorders and Differences Between Populations.

ABSTRACT: Background: Nitrous oxide (N₂O), commonly known as laughing gas, is inhaled recreationally because it produces the feelings of euphoria and freedom from pain. The risk of neurological dysfunction secondary to N₂O abuse and its clinical diagnosis are, however, not yet sufficiently recognized, especially in China. Here, we have summarized the key clinical characteristics of N₂O-induced neurological disorders. Materials and Methods: We recruited 20 patients with N₂O-induced neurological disorders and analyzed their clinical features, laboratory data, magnetic resonance imaging and electromyography. We also carried out a literature review and compared 99 previously reported patients with our case series to confirm our results. Subgroup

SUBMITTER: Zhang J 

PROVIDER: S-EPMC8110825 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature