Neural responses to viewing human faces in autism spectrum disorder: A quantitative meta-analysis of two decades of research.

ABSTRACT: The human face communicates a wealth of socially relevant information such as person identity, emotion, and intention. A consistent behavioral finding in autism spectrum disorder (ASD) is reduced attention to or difficulty drawing meaning from faces. However, neuroimaging research into the neural correlates of face processing differences in ASD has returned mixed results. While many studies find hypo-activation or hypo-connectivity of core and extended face network regions, others show hyper-activation, equal activation, or even activation shifted to object-selective fusiform gyrus (FG) regions in ASD during face processing. This study consolidates two decades of literature to reveal common and consistent patterns of brain activation when viewing human faces in ASD. It also addresses wheth

SUBMITTER: Ammons CJ 

PROVIDER: S-EPMC8111365 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature