Biomarkers predictive of treatment response in psoriasis and psoriatic arthritis: a systematic review.

ABSTRACT:

Aims

The ability to predict response to treatment remains a key unmet need in psoriatic disease. We conducted a systematic review of studies relating to biomarkers associated with response to treatment in either psoriasis vulgaris (PsV) or psoriatic arthritis (PsA).

Methods

A search was conducted in PubMed, Embase and the Cochrane library from their inception to 2 September 2020, and conference proceedings from four major rheumatology conferences. Original research articles studying pre-treatment biomarker levels associated with subsequent response to pharmacologic treatment in either PsV or PsA were included.

Results

A total of 765 articles were retrieved and after review, 44 articles (22 relating to PsV and 22 to PsA) met the systematic review's eligibility criteria

SUBMITTER: Magee C 

PROVIDER: S-EPMC8111521 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature