Awake prone positioning for hypoxaemic respiratory failure: past, COVID-19 and perspectives.

ABSTRACT: Prone positioning reduces mortality in the management of intubated patients with moderate-to-severe acute respiratory distress syndrome. It allows improvement in oxygenation by improving ventilation/perfusion ratio mismatching.Because of its positive physiological effects, prone positioning has also been tested in non-intubated, spontaneously breathing patients, or "awake" prone positioning. This review provides an update on awake prone positioning for hypoxaemic respiratory failure, in both coronavirus disease 2019 (COVID-19) and non-COVID-19 patients. In non-COVID-19 acute respiratory failure, studies are limited to a few small nonrandomised studies and involved patients with different diseases. However, results have been appealing with regard to oxygenation improvement, especially when

SUBMITTER: Touchon F 

PROVIDER: S-EPMC8112009 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature