A community divided: Post-transplant live vaccine practices among Society of Pediatric Liver Transplantation (SPLIT) centers.

ABSTRACT:

Background

Historically, the IDSA and the AST have recommended that live vaccines not be administered post-transplant due to concern for induction of vaccine-strain disease in immunocompromised hosts. However, recent prospective studies and revised AST guidelines published in April 2019 suggest that in the current era of immunosuppression minimization, live vaccines may be safely administered to select transplant recipients with resulting immunoprotection. The goal of this study was to assess current post-transplant live vaccine practices at individual pediatric liver transplant centers following the updated AST guidelines.

Methods

A six-item email survey detailing center-specific post-transplant live vaccine practices followed by up to three response-specific questions were

SUBMITTER: Kemme S 

PROVIDER: S-EPMC8112257 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature