A comparative analysis of important public clinical trial registries, and a proposal for an interim ideal one.

ABSTRACT:

Background

It is an ethical and scientific obligation to register each clinical trial, and report its results, accurately, comprehensively and on time. The WHO recognizes 17 public registries as Primary Registries, and has also introduced a set of minimal standards in the International Standards for Clinical Trial Registries (ISCTR) that primary registries need to implement. These standards are categorized into nine sections-Content, Quality and Validity, Accessibility, Unambiguous Identification, Technical Capacity, Administration and Governance, the Trial Registration Data Set (TRDS), Partner registries and Data Interchange Standards. This study compared the WHO's primary registries, and the US's ClinicalTrials.gov, to examine the implementation of ISCTR, with the aim of defining

SUBMITTER: Venugopal N 

PROVIDER: S-EPMC8112656 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature