Integrative Review of Early Life Adversity and Cortisol Regulation in Pregnancy.

ABSTRACT:

Objective

To synthesize published findings on the relationship between early life adversity and hypothalamic-pituitary-adrenal axis cortisol parameters in pregnant women.

Data sources

We searched PubMed, CINAHL, and PsycINFO databases using variants and combinations of the keywords early life adversity, pregnancy, hypothalamic-pituitary-adrenal axis, and cortisol.

Study selection

We selected articles that included pregnant participants, included measures of cortisol and early life adversity, were published in English in a peer-reviewed journal, and were of sufficient methodologic quality. Date of publication was unrestricted through May 2020.

Data extraction

Twenty-five articles met the inclusion criteria and were evaluated for quality and risk of bias. Sources

SUBMITTER: Epstein CM 

PROVIDER: S-EPMC8113070 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature