Disinhibition of right inferior frontal gyrus underlies alpha asymmetry in women with low testosterone.

ABSTRACT: Asymmetrical expression of alpha oscillations in the frontal cortex, increased left relative to right, is a phenotype associated with increased behavioral inhibition and mood-related psychiatric illnesses. However, investigations of frontal alpha asymmetry in mood-disorders have yielded inconsistent findings. A better understanding of factors that contribute to individual differences is required to establish a useful biomarker for the diagnosis and treatment of mood and stress related disorders. A novel factor is hormone concentration, as steroid hormones play a prominent role in regulating mood and stress. To investigate this question, concentrations of testosterone and estradiol were sampled. Multiple linear regression revealed that low levels of testosterone correlated with greater fron

SUBMITTER: Riddle J 

PROVIDER: S-EPMC8113111 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature