Diabetes subgroups and risk for complications: The Multi-Ethnic Study of Atherosclerosis (MESA).

ABSTRACT:

Aims

To characterize diabetes subgroups among a multi-ethnic cohort and assess risk for incident complications.

Methods

We included 1587 participants from the Multi-Ethnic Study of Atherosclerosis with diabetes. We characterized eight diabetes subgroups according to absolute thresholds for disease characteristics: age at diabetes diagnosis (≤45 years), fasting glucose (FG ≥7.7 mmol/L; ≥140 mg/dL), and waist circumference (women ≥105 cm; men ≥110 cm). We estimated risk for mortality, incident cardiovascular disease, chronic kidney disease, heart failure, dementia, and retinopathy, respectively, over 17 years after adjustment for demographics, behavioral, clinical risk factors, and cohort attrition.

Results

The subgroup with both high FG and early age at onset was assoc

SUBMITTER: Bancks MP 

PROVIDER: S-EPMC8113152 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature