Review of Prognostic Expression Markers for Clear Cell Renal Cell Carcinoma.

ABSTRACT: Context: The number of prognostic markers for clear cell renal cell carcinoma (ccRCC) has been increasing regularly over the last 15 years, without being integrated and compared. Objective: Our goal was to perform a review of prognostic markers for ccRCC to lay the ground for their use in the clinics. Evidence Acquisition: PubMed database was searched to identify RNA and protein markers whose expression level was reported as associated with survival of ccRCC patients. Relevant studies were selected through cross-reading by two readers. Evidence Synthesis: We selected 249 studies reporting an association with prognostic of either single markers or multiple-marker models. Altogether, these studies were based on a total of 341 distinct markers and 13 multiple-marke

SUBMITTER: Petitprez F 

PROVIDER: S-EPMC8113694 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature