Identification of Zoophilic Dermatophytes Using MALDI-TOF Mass Spectrometry.

ABSTRACT: Dermatophytoses represent a major health burden in animals and man. Zoophilic dermatophytes usually show a high specificity to their original animal host but a zoonotic transmission is increasingly recorded. In humans, these infections elicit highly inflammatory skin lesions requiring prolonged therapy even in the immunocompetent patient. The correct identification of the causative agent is often crucial to initiate a targeted and effective therapy. To that end, matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) represents a promising tool. The objective of this study was to evaluate the reliability of species identification of zoophilic dermatophytes using MALDI-TOF MS. The investigation of isolates from veterinary clinical samples suspicious of de

SUBMITTER: Baumbach CM 

PROVIDER: S-EPMC8113951 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature