Implementing radical cure diagnostics for malaria: user perspectives on G6PD testing in Bangladesh.

ABSTRACT:

Background

The radical cure of Plasmodium vivax requires treatment with an 8-aminoquinoline drug, such as primaquine and tafenoquine, to eradicate liver hypnozoite stages, which can reactivate to cause relapsing infections. Safe treatment regimens require prior screening of patients for glucose-6-phosphate dehydrogenase (G6PD) deficiency to avoid potential life-threatening drug induced haemolysis. Testing is rarely available in malaria endemic countries, but will be needed to support routine use of radical cure. This study investigates end-user perspectives in Bangladesh on the introduction of a quantitative G6PD test (SD Biosensor STANDARD™ G6PD analyser) to support malaria elimination.

Methods

The perspectives of users on the SD Biosensor test were analysed using semi-stru

SUBMITTER: Engel N 

PROVIDER: S-EPMC8114691 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature