Validation of the liver traffic light test as a predictive model for survival and development of liver-related events.

ABSTRACT:

Background and aim

Liver disease mortality rates continue to rise due to late diagnosis. We need noninvasive tests to be made available in the community that can identify patients at risk from a serious liver-related event (SLE). We examine the performance of a blood test, the liver traffic light test (LTLT), with regard to its ability to predict survival and SLEs.

Methods

Using routinely gathered clinical data, sequential LTLT test results from 4854 individuals with suspected liver disease were prospectively analyzed (median follow-up 41 months). An SLE was defined as the development of cirrhosis, liver failure, ascites, or varices. Patients were graded as follows: red (high risk), amber (intermediate risk), and green (low risk).

Results

Overall, 565 individuals expe

SUBMITTER: Sylvester R 

PROVIDER: S-EPMC8114996 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature