Bioinspired Polymeric High Aspect Ratio Particles with Asymmetric Janus Functionalities.

ABSTRACT: Polymeric particles with intricate morphologies and properties have been developed based on bioinspired designs for applications in regenerative medicine, tissue engineering, and drug delivery. However, the fabrication of particles with asymmetric functionalities remains a challenge. Janus polymeric particles are an emerging class of material with asymmetric functionalities; however, they are predominantly spherical in morphology, made from non-biocompatible materials, and made using specialized fabrication techniques. We therefore set out to fabricate nonspherical Janus particles inspired by high aspect ratio filamentous bacteriophage using polycaprolactone polymers and standard methods. Janus high aspect ratio particles (J-HARPs) were fabricated with a nanotemplating technique to create

SUBMITTER: Finbloom JA 

PROVIDER: S-EPMC8115014 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature