Long-term impact of a ten-year intervention program on human and canine Trypanosoma cruzi infection in the Argentine Chaco.

ABSTRACT:

Background

Interruption of domestic vector-borne transmission of Trypanosoma cruzi is still an unmet goal in several American countries. In 2007 we launched a long-term intervention program aimed to suppress house infestation with the main domestic vector in southern South America (Triatoma infestans) and domestic transmission in Pampa del Indio, a resource-constrained, hyperendemic municipality with 1446 rural houses inhabited by Creole and indigenous people, in the Argentine Chaco ecoregion. Here, we assessed whether the 10-year insecticide-based program combined with community mobilization blocked vector-borne domestic transmission of T. cruzi to humans and dogs.

Methods

We carried out two municipality-wide, cross-sectional serosurveys of humans and dogs (considered senti

SUBMITTER: Cardinal MV 

PROVIDER: S-EPMC8115854 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature