PEER systematic review of randomized controlled trials: Management of chronic neuropathic pain in primary care.

ABSTRACT:

Objective

To determine the proportion of patients with neuropathic pain who achieve a clinically meaningful improvement in their pain with the use of different pharmacologic and nonpharmacologic treatments.

Data sources

MEDLINE, EMBASE, the Cochrane Library, and a gray literature search.

Study selection

Randomized controlled trials that reported a responder analysis of adults with neuropathic pain-specifically diabetic neuropathy, postherpetic neuralgia, or trigeminal neuralgia-treated with any of the following 8 treatments: exercise, acupuncture, serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), topical rubefacients, opioids, anticonvulsant medications, and topical lidocaine.

Synthesis

A total of 67 randomized controlled t

SUBMITTER: Falk J 

PROVIDER: S-EPMC8115961 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature