Effects of Cannabinoids on Sleep and their Therapeutic Potential for Sleep Disorders.

ABSTRACT: The recent trend for legalization of medicinal cannabis and cannabinoid-containing products, together with their soporific effects, has led to a surge of interest of their potential therapeutic role in the management of some common sleep disorders, such as insomnia, sleep disordered breathing, and restless legs syndrome, and less common disorders such as narcolepsy and parasomnias. Although much of the pre-clinical and clinical data were derived from studies with relatively small sample sizes and limited by biases in assessment, and in clinical trials lack of allocation concealment, as a whole, the results indicate a potential therapeutic role for cannabinoids in the management of some sleep disorders. Clinical trials are underway for insomnia and obstructive sleep apnea management, but th

SUBMITTER: Kaul M 

PROVIDER: S-EPMC8116407 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature