Cure lies in nature: medicinal plants and endophytic fungi in curbing cancer.

ABSTRACT: Success of targeted cancer treatment modalities has generated an ambience of plausible cure for cancer. However, cancer remains to be the major cause of mortality across the globe. The emergence of chemoresistance, relapse after treatment and associated adverse effects has posed challenges to the present therapeutic regimes. Thus, investigating new therapeutic agents of natural origin and delineating the underlying mechanism of action is necessary. Since ages and still in continuum, the phytochemicals have been the prime source of identifying bioactive agents against cancer. They have been exploited for isolating targeted specific compounds to modulate the key regulating signaling pathways of cancer pathogenesis and progression. Capsaicin (alkaloid compound in chilli), catechin, epicatechi

SUBMITTER: Tyagi G 

PROVIDER: S-EPMC8116431 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature