Genome-Wide Detection of Runs of Homozygosity in Laiwu Pigs Revealed by Sequencing Data.

ABSTRACT: Laiwu pigs, distinguished by their high intramuscular fat of 7-9%, is an indigenous pig breed of China, and recent studies also found that Laiwu pigs showed high resistance to Porcine circovirus type 2. However, with the introduction of commercial varieties, the population of Laiwu pigs has declined, and some lineages have disappeared, which could result in inbreeding. Runs of homozygosity (ROH) can be used as a good measure of individual inbreeding status and is also normally used to detect selection signatures so as to map the candidate genes associated with economically important traits. In this study, we used data from Genotyping by Genome Reducing and Sequencing to investigate the number, length, coverage, and distribution patterns of ROH in 93 Chinese Laiwu pigs and identified genomi

SUBMITTER: Fang Y 

PROVIDER: S-EPMC8116706 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature