NCCBM, a Nomogram Prognostic Model in Breast Cancer Patients With Brain Metastasis.

ABSTRACT: Purpose: Nomogram prognostic models could greatly facilitate risk stratification and treatment strategies for cancer patients. We developed and validated a new nomogram prognostic model, named NCCBM, for breast cancer patients with brain metastasis (BCBM) using a large BCBM cohort from the SEER (Surveillance, Epidemiology, and End Results) database. Patients and Methods: Clinical data for 975 patients diagnosed from 2011 to 2014 were used to develop the nomogram prognostic model. The predictive accuracy and discriminative ability of the nomogram were determined by concordance index (C-index) and calibration curve. The results were validated using an independent cohort of 542 BCBM patients diagnosed from 2014 to 2015. Results: The following variables were selected in th

SUBMITTER: Liu Q 

PROVIDER: S-EPMC8116746 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature