From Prokaryotes to Eukaryotes: Insights Into the Molecular Structure of Glycogen Particles.

ABSTRACT: Glycogen is a highly-branched polysaccharide that is widely distributed across the three life domains. It has versatile functions in physiological activities such as energy reserve, osmotic regulation, blood glucose homeostasis, and pH maintenance. Recent research also confirms that glycogen plays important roles in longevity and cognition. Intrinsically, glycogen function is determined by its structure that has been intensively studied for many years. The recent association of glycogen α-particle fragility with diabetic conditions further strengthens the importance of glycogen structure in its function. By using improved glycogen extraction procedures and a series of advanced analytical techniques, the fine molecular structure of glycogen particles in human beings and several model organi

SUBMITTER: Liu QH 

PROVIDER: S-EPMC8116748 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature