Systematic Review and Meta-analysis of Herpes Zoster Vaccine in Patients With CKD.

ABSTRACT:

Introduction

Chronic kidney disease (CKD) is a risk factor for herpes zoster (HZ) infection. Few studies have examined HZ vaccine (HZV) in this population. We conducted a systematic review and meta-analysis investigating the efficacy and safety of HZV in patients with renal disease (CKD, dialysis, and transplant).

Methods

MEDLINE, Embase, and Cochrane Central Register of Controlled Trials (CENTRAL) databases (up to May 2020) were searched for randomized controlled trials and nonrandomized controlled studies evaluating HZV in patients with CKD for effectiveness and adverse event risks. Studies without a control group (placebo or no vaccine) were excluded. Extraction of prespecified data and risk of bias assessments using the Newcastle-Ottawa scale for cohort studies and the C

SUBMITTER: Hamad MA 

PROVIDER: S-EPMC8116755 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature