Development and Characterization of High-Throughput Caenorhabditis elegans - Enterococcus faecium Infection Model.

ABSTRACT: The genus Enterococcus includes two Gram-positive pathogens of particular clinical relevance: E. faecalis and E. faecium. Infections with each of these pathogens are becoming more frequent, particularly in the case of hospital-acquired infections. Like most other bacterial species of clinical importance, antimicrobial resistance (and, specifically, multi-drug resistance) is an increasing threat, with both species considered to be of particular importance by the World Health Organization and the US Centers for Disease Control. The threat of antimicrobial resistance is exacerbated by the staggering difference in the speeds of development for the discovery and development of the antimicrobials versus resistance mechanisms. In the search for alternative strategies, modulat

SUBMITTER: Revtovich AV 

PROVIDER: S-EPMC8116795 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature