Efficacy of Phage- and Bacteriocin-Based Therapies in Combatting Nosocomial MRSA Infections.

ABSTRACT: Staphylococcus aureus is a pathogen commonly found in nosocomial environments where infections can easily spread - especially given the reduced immune response of patients and large overlap between personnel in charge of their care. Although antibiotics are available to treat nosocomial infections, the increased occurrence of antibiotic resistance has rendered many treatments ineffective. Such is the case for methicillin resistant S. aureus (MRSA), which has continued to be a threat to public health since its emergence. For this reason, alternative treatment technologies utilizing antimicrobials such as bacteriocins, bacteriophages (phages) and phage endolysins are being developed. These antimicrobials provide an advantage over antibiotics in that many have narrow inhibition

SUBMITTER: Walsh L 

PROVIDER: S-EPMC8116899 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature