Comparison of single-voxel ¹H-cardiovascular magnetic resonance spectroscopy techniques for in vivo measurement of myocardial creatine and triglycerides at 3T.

ABSTRACT:

Background

Single-voxel proton cardiovascular magnetic resonance spectroscopy (¹H-CMRS) benefits from 3 T to detect metabolic abnormalities with the quantification of intramyocardial fatty acids (FA) and creatine (Cr). Conventional point resolved spectroscopy (PRESS) sequence remains the preferred choice for CMRS, despite its chemical shift displacement error (CSDE) at high field (≥ 3 T). Alternative candidate sequences are the semi-adiabatic Localization by Adiabatic SElective Refocusing (sLASER) recommended for brain and musculoskeletal applications and the localized stimulated echo acquisition mode (STEAM). In this study, we aim to compare these three single-voxel ¹H-CMRS techniques: PRESS, sLASER and STEAM for reproducible quantification of myocardial FA a

SUBMITTER: Sourdon J 

PROVIDER: S-EPMC8117273 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature