A Novel Method to Treat Progressive Desmoid Tumors Involving Neurovascular Bundles: A Retrospective Cohort Study.

ABSTRACT:

Background

More effective therapies are needed to treat progressive desmoid tumors when active surveillance and systemic therapy fail.

Objective

To assess the efficacy and safety of sandwich isolation surgery on the local control of progressive desmoid tumors involving neurovascular bundles.

Methods

A total of 27 patients with progressive desmoid tumors at extremities involving neurovascular bundles who received surgery at our hospital between August 2014 and August 2018 were identified. A total of 13 patients received sandwich isolation surgery, in which R2 resection was performed in neurovasculature-involving regions, and a biomaterial patch was used to envelop involved neurovascular structures and isolate residual tumors. In non-neurovasculature-involving regions,

SUBMITTER: Yin JQ 

PROVIDER: S-EPMC8117464 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature