The impact of quorum sensing on the modulation of phage-host interactions.

ABSTRACT: Bacteriophages are the most diverse and abundant biological entities on the Earth and require host bacteria to replicate. Because of this obligate relationship, in addition to the challenging conditions of surrounding environments, phages must integrate information about extrinsic and intrinsic factors when infecting their host. This integration helps to determine whether the infection becomes lytic or lysogenic, which likely influences phage spreading and long-term survival. Although a variety of environmental and physiological clues are known to modulate lysis-lysogeny decisions, the social interplay among phages and host populations has been overlooked until recently. A growing body of evidence indicates that cell-cell communication in bacteria and, more recently, peptide-based communic

SUBMITTER: Leon-Felix J 

PROVIDER: S-EPMC8117525 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature