Colon cancer survival differs from right side to left side and lymph node harvest number matter.

ABSTRACT:

Background

Right-sided colorectal cancer (CRC) has worse survival than does left-sided CRC. The objective of this study was to further assess the impact of right-side location on survival and the role of the extent of lymphadenectomy.

Methods

All CRCs diagnosed between 2000 and 2012 in Emilia-Romagna Region, Italy, were included. Data for stage, grade, histology, screening history, and number of removed lymph nodes (LN) were collected. Multivariable Cox regression models were used to estimate hazard ratios (HR), with relative 95% confidence intervals (95%CI), of right vs. left colon and of removing < 12, 12-21 or > 21 lymph nodes by cancer site.

Results

During the study period, 29,358 patients were registered (8828 right colon, 18,852 left colon, 1678 transverse). Pat

SUBMITTER: Mangone L 

PROVIDER: S-EPMC8117551 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature