Genome wide association study of response to interval and continuous exercise training: the Predict-HIIT study.

ABSTRACT:

Background

Low cardiorespiratory fitness (V̇O_2peak) is highly associated with chronic disease and mortality from all causes. Whilst exercise training is recommended in health guidelines to improve V̇O_2peak, there is considerable inter-individual variability in the V̇O_2peak response to the same dose of exercise. Understanding how genetic factors contribute to V̇O_2peak training response may improve personalisation of exercise programs. The aim of this study was to identify genetic variants that are associated with the magnitude of V̇O₂peak response following exercise training.

Methods

Participant change in objectively measured V̇O₂peak from 18 different interventions was obtained from a multi-centre study (Predi

SUBMITTER: Williams CJ 

PROVIDER: S-EPMC8117553 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature